Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pou4f1  POU domain, class 4, transcription factor 1   (Synonyms: Brn3, Brn-3, Brn-3.0, Brn3a, E130119J07Rik)
Results	Reference
1	J:187218 Andersson LS, Larhammar M, Memic F, Wootz H, Schwochow D, Rubin CJ, Patra K, Arnason T, Wellbring L, Hjalm G, Imsland F, Petersen JL, McCue ME, Mickelson JR, Cothran G, Ahituv N, Roepstorff L, Mikko S, Vallstedt A, Lindgren G, Andersson L, Kullander K, Mutations in DMRT3 affect locomotion in horses and spinal circuit function in mice. Nature. 2012 Aug 30;488(7413):642-6
1	J:166443 Avraham O, Hadas Y, Vald L, Hong S, Song MR, Klar A, Motor and dorsal root ganglion axons serve as choice points for the ipsilateral turning of dI3 axons. J Neurosci. 2010 Nov 17;30(46):15546-57
1	J:180432 D'Autreaux F, Coppola E, Hirsch MR, Birchmeier C, Brunet JF, Homeoprotein Phox2b commands a somatic-to-visceral switch in cranial sensory pathways. Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20018-23
1*	J:211182 Deng M, Yang H, Xie X, Liang G, Gan L, Comparative expression analysis of POU4F1, POU4F2 and ISL1 in developing mouse cochleovestibular ganglion neurons. Gene Expr Patterns. 2014 May;15(1):31-7
1	J:175535 Deng Q, Andersson E, Hedlund E, Alekseenko Z, Coppola E, Panman L, Millonig JH, Brunet JF, Ericson J, Perlmann T, Specific and integrated roles of Lmx1a, Lmx1b and Phox2a in ventral midbrain development. Development. 2011 Aug;138(16):3399-408
1*	J:85580 Fedtsova N, Perris R, Turner EE, Sonic hedgehog regulates the position of the trigeminal ganglia. Dev Biol. 2003 Sep 15;261(2):456-69
1	J:252092 Gard C, Gonzalez Curto G, Frarma YE, Chollet E, Duval N, Auzie V, Aurade F, Vigier L, Relaix F, Pierani A, Causeret F, Ribes V, Pax3- and Pax7-mediated Dbx1 regulation orchestrates the patterning of intermediate spinal interneurons. Dev Biol. 2017 Dec 1;432(1):24-33
1*	J:70696 Gowan K, Helms AW, Hunsaker TL, Collisson T, Ebert PJ, Odom R, Johnson JE, Crossinhibitory activities of ngn1 and math1 allow specification of distinct dorsal interneurons. Neuron. 2001 Aug;31(2):219-32
1	J:305179 Gray de Cristoforis A, Ferrari F, Clotman F, Vogel T, Differentiation and localization of interneurons in the developing spinal cord depends on DOT1L expression. Mol Brain. 2020 May 29;13(1):85
1	J:153219 Grossmann KS, Wende H, Paul FE, Cheret C, Garratt AN, Zurborg S, Feinberg K, Besser D, Schulz H, Peles E, Selbach M, Birchmeier W, Birchmeier C, The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16704-9
1*	J:331142 Han P, She Y, Yang Z, Zhuang M, Wang Q, Luo X, Yin C, Zhu J, Jaffrey SR, Ji SJ, Cbln1 regulates axon growth and guidance in multiple neural regions. PLoS Biol. 2022 Nov;20(11):e3001853
1	J:226479 Hua ZL, Emiliani FE, Nathans J, Rac1 plays an essential role in axon growth and guidance and in neuronal survival in the central and peripheral nervous systems. Neural Dev. 2015;10(1):21
1	J:208415 Inamata Y, Shirasaki R, Dbx1 triggers crucial molecular programs required for midline crossing by midbrain commissural axons. Development. 2014 Mar;141(6):1260-71
1	J:150348 Iulianella A, Sharma M, Vanden Heuvel GB, Trainor PA, Cux2 functions downstream of Notch signaling to regulate dorsal interneuron formation in the spinal cord. Development. 2009 Jul;136(14):2329-34
1	J:226834 Jones I, Hagglund AC, Tornqvist G, Nord C, Ahlgren U, Carlsson L, A novel mouse model of tuberous sclerosis complex (TSC): eye-specific Tsc1-ablation disrupts visual-pathway development. Dis Model Mech. 2015 Dec 1;8(12):1517-29
1	J:88407 Knabe W, Knerlich F, Washausen S, Kietzmann T, Siren AL, Brunnett G, Kuhn HJ, Ehrenreich H, Expression patterns of erythropoietin and its receptor in the developing midbrain. Anat Embryol (Berl). 2004 Mar;207(6):503-12
1	J:143462 Liu Z, Li H, Hu X, Yu L, Liu H, Han R, Colella R, Mower GD, Chen Y, Qiu M, Control of precerebellar neuron development by Olig3 bHLH transcription factor. J Neurosci. 2008 Oct 1;28(40):10124-33
1	J:239944 Lorenzen SM, Duggan A, Osipovich AB, Magnuson MA, Garcia-Anoveros J, Insm1 promotes neurogenic proliferation in delaminated otic progenitors. Mech Dev. 2015 Nov;138 Pt 3:233-45
1	J:310819 Makrides N, Panayiotou E, Fanis P, Karaiskos C, Lapathitis G, Malas S, Sequential Role of SOXB2 Factors in GABAergic Neuron Specification of the Dorsal Midbrain. Front Mol Neurosci. 2018;11:152
1	J:206629 Marklund U, Alekseenko Z, Andersson E, Falci S, Westgren M, Perlmann T, Graham A, Sundstrom E, Ericson J, Detailed expression analysis of regulatory genes in the early developing human neural tube. Stem Cells Dev. 2014 Jan 1;23(1):5-15
1	J:124115 Nakatani T, Minaki Y, Kumai M, Ono Y, Helt determines GABAergic over glutamatergic neuronal fate by repressing Ngn genes in the developing mesencephalon. Development. 2007 Aug;134(15):2783-93
1	J:295953 Niu X, Liu L, Wang T, Chuan X, Yu Q, Du M, Gu Y, Wang L, Mapping of Extrinsic Innervation of the Gastrointestinal Tract in the Mouse Embryo. J Neurosci. 2020 Aug 26;40(35):6691-6708
1	J:207511 Paixao S, Balijepalli A, Serradj N, Niu J, Luo W, Martin JH, Klein R, EphrinB3/EphA4-mediated guidance of ascending and descending spinal tracts. Neuron. 2013 Dec 18;80(6):1407-20
1	J:96926 Pan L, Yang Z, Feng L, Gan L, Functional equivalence of Brn3 POU-domain transcription factors in mouse retinal neurogenesis. Development. 2005 Feb;132(4):703-12
1	J:162166 Peltopuro P, Kala K, Partanen J, Distinct requirements for Ascl1 in subpopulations of midbrain GABAergic neurons. Dev Biol. 2010 Jul 1;343(1-2):63-70
1	J:89367 Puelles E, Annino A, Tuorto F, Usiello A, Acampora D, Czerny T, Brodski C, Ang SL, Wurst W, Simeone A, Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain. Development. 2004 May;131(9):2037-48
1	J:184845 Quina LA, Tempest L, Hsu YW, Cox TC, Turner EE, Hmx1 is required for the normal development of somatosensory neurons in the geniculate ganglion. Dev Biol. 2012 May 1;365(1):152-63
1	J:149456 Rocha SF, Lopes SS, Gossler A, Henrique D, Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity. Dev Biol. 2009 Apr 1;328(1):54-65
1	J:271110 Ruiz-Reig N, Rakotobe M, Bethus I, Le Menn G, Huditz HI, Marie H, Lamonerie T, D'Autreaux F, Developmental Requirement of Homeoprotein Otx2 for Specific Habenulo-Interpeduncular Subcircuits. J Neurosci. 2019 Feb 6;39(6):1005-1019
1	J:314775 Sagner A, Zhang I, Watson T, Lazaro J, Melchionda M, Briscoe J, A shared transcriptional code orchestrates temporal patterning of the central nervous system. PLoS Biol. 2021 Nov;19(11):e3001450
1	J:166950 Shi M, Zheng MH, Liu ZR, Hu ZL, Huang Y, Chen JY, Zhao G, Han H, Ding YQ, DCC is specifically required for the survival of retinal ganglion and displaced amacrine cells in the developing mouse retina. Dev Biol. 2010 Dec 1;348(1):87-96
1	J:143526 Storm R, Cholewa-Waclaw J, Reuter K, Brohl D, Sieber M, Treier M, Muller T, Birchmeier C, The bHLH transcription factor Olig3 marks the dorsal neuroepithelium of the hindbrain and is essential for the development of brainstem nuclei. Development. 2009 Jan;136(2):295-305
1*	J:284490 Varum S, Baggiolini A, Zurkirchen L, Atak ZK, Cantu C, Marzorati E, Bossart R, Wouters J, Hausel J, Tuncer E, Zingg D, Veen D, John N, Balz M, Levesque MP, Basler K, Aerts S, Zamboni N, Dummer R, Sommer L, Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation. Cell Stem Cell. 2019 Apr 4;24(4):637-653.e9
1*	J:277247 Vetrivel S, Tiso N, Kugler A, Irmler M, Horsch M, Beckers J, Hladik D, Giesert F, Gailus-Durner V, Fuchs H, Sabrautzki S, Adler T, Treise I, Busch DH, Aguilar-Pimentel A, Ollert M, Gotz A, Amarie OV, Stoeger T, Schulz H, Becker L, Klopstock T, Schrewe A, Spielmann N, Bekeredjian R, Garrett L, Holter SM, Zimprich A, Wurst W, Mayer-Kuckuk P, Hans W, Rozman J, Klingenspor M, Neff F, da Silva-Buttkus P, Calzada-Wack J, Racz I, Zimmer A, Rathkolb B, Wolf E, Prehn C, Adamski J, Ostereicher M, Miller G, Steinkamp R, Lengger C, Maier H, Stoeger C, Leuchtenberger S, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Hrabe de Angelis M, Graw J, Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia. Exp Eye Res. 2019 Apr 13;
1*	J:107704 Xiang M, Requirement for Brn-3b in early differentiation of postmitotic retinal ganglion cell precursors. Dev Biol. 1998 May 15;197(2):155-69
1	J:195640 Xu J, Nonogaki M, Madhira R, Ma HY, Hermanson O, Kioussi C, Gross MK, Population-specific regulation of Chmp2b by Lbx1 during onset of synaptogenesis in lateral association interneurons. PLoS One. 2012;7(12):e48573
1*	J:332134 Zang Y, Chaudhari K, Bashaw GJ, Tace/ADAM17 is a bi-directional regulator of axon guidance that coordinates distinct Frazzled and Dcc receptor signaling outputs. Cell Rep. 2022 Dec 6;41(10):111785
1	J:183949 Zou M, Li S, Klein WH, Xiang M, Brn3a/Pou4f1 regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord. Dev Biol. 2012 Apr 15;364(2):114-27